October 29, 2013

Prof. Adam Siepel ’94 Tracks Evolutionary Changes in Human Genome

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By YVONNE HUANG

Although large projects such as the human genome project and the Encyclopedia of DNA Elements, also known as ENCODE, have sequenced and catalogued the portions of the human genome that have a known function, only the protein coding regions of the genome have been extensively studied, which make up two percent of the entire genome.

Prof. Adam Siepel ’94, biological statistics and computational biology, explores evolution through genetics by using data compiled from different sources to track the evolutionary changes in both the regulatory sequences and the protein-coding sequences of the genome.

Liz Camuti / Associate EditorExploring evolution | Prof. Adam Siepel ’94, biological statistics and computational biology, uses genetic databases to uncover the evolution of transcription factors in the human genome.

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