NEW YORK (AP) — Tom Glavine put the New York Mets in a huge hole Sunday and they never climbed back out.

The 303-game winner was chased in the first inning, charged with all seven of Florida's early runs. He made a throwing error and hit Marlins lefty Dontrelle Willis with a pitch with the bases loaded, mistakes that symbolized the Mets' September collapse.

Glavine hoped to pitch the Mets into the playoffs on the final day of the regular season. Instead, he managed only one out in the second-shortest start of his brilliant career. New York lost 8-1 and missed the playoffs when Philadelphia beat Washington 6-1 to take the NL East title.

"We had an opportunity to win this thing and we let it get away from us," Glavine said. "You don't like to give away games. Obviously, over the last six weeks, we did quite a lot of that."

The seven runs matched the most Glavine allowed in an inning during his 21-year career, the Elias Sports Bureau said. He also gave up seven to Colorado in 1996.

This flop could end up being Glavine's final outing on a major league mound if the 41-year-old left-hander decides to retire — or at least his last one for the Mets if he chooses to pitch elsewhere next season. Glavine has a $13 million player option for next year with a $3 million buyout.

"I want to go home and figure out what I want to do," he said.

Glavine got ahead 0-2 on leadoff batter Hanley Ramirez, then threw a pitch that glanced off Ramirez's forearm. But plate umpire Joe West ruled that Ramirez didn't attempt to get out of the way, so he wasn't awarded first base.

Ramirez wound up walking and after Dan Uggla grounded into a force play, Glavine didn't get another out. Jeremy Hermida singled, Miguel Cabrera hit an RBI single and Cody Ross punched a two-run double to right.

Ross headed for third on the throw home. The ball squirted away from catcher Ramon Castro and Glavine picked it up, but fired wide of third for an error that made it 4-0.

Mike Jacobs looped a single, Matt Treanor walked and Alejandro De Aza singled to load the bases. Glavine then plunked Willis with a 1-2 delivery, forcing home another run.

"The one at-bat I really want back is Dontrelle," Glavine said. "I tried to throw a changeup in and it just kind of got away. But I don't think with the others my sequence or location would have been any different."

Glavine, a two-time Cy Young Award winner who earned his 300th win in August, was lifted for Jorge Sosa and booed loudly by the sold-out crowd as he walked off the mound. After striking out Ramirez, Sosa gave up a two-run double to Uggla that made it 7-0.

"Early on, I just wanted to get a groundball," Glavine said. "Unfortunately, I got three of them — one wasn't hard enough to the turn the double play and the other two found holes."

New York scored in the bottom of the first on Willis' wild pitch and had the bases loaded when Ramon Castro hit a long drive to left field. Thinking it was gone, Castro raised his index finger in the air. But Ross made the catch on the warning track and let out a deep breath.

The Mets lost slugger Carlos Delgado to a broken left hand when he was hit by Willis' pitch in the first. Delgado stayed in the game to run, then was replaced at first base by Jeff Conine in the second inning.

New York also stranded two in the second and left the bases loaded in the third without scoring.

A wild Willis was pulled after walking five in 2 2-3 innings. He entered 11-3 with a 2.49 ERA in 18 career starts against the Mets — including 5-0 at Shea Stadium.

Glavine failed to get an out on May 16, 1989, with Atlanta at the Chicago Cubs. He threw only seven pitches in that game, allowing four runs — three earned — and four hits. He departed after spraining his left ankle while covering first base.

The last time the Mets gave up seven runs in the first inning was July 31, 1999, at the Cubs.

"I'm not devastated. I'm disappointed. Devastation is for much greater things in life," Glavine said.